The average yearly salary for Medical Assistant in Trenton, Illinois is $30,265. If you are just beginning to work a new job as a Medical Assistant in Trenton, Illinois, you could earn a starting pay rate of $24,924 annually. As is true for most jobs and careers, you can expect your hourly pay rate or salary to increase as you gain experience and the longer you are employed with the same employer. In Trenton you could potentially make an average income of around $35,606 after several years on the job with increased wages. When pursuing your career of choice, you should compare salaries of similar professions and factor in variables such as health benefits and potential for raises and promotions over time.